Weight Loss Drug Ozempic Increases Risk of Suicide, Study Finds

Andrew Anglin August 21, 2024

Probably, fat people get depressed just from not eating. So if you give them drugs to make them not eat, of course they’re going to be more likely to kill themselves.

I would also wager that fat people have much lower suicide rates generally, and so if people lose weight for any reason, they become more likely to kill themselves.

Of course, it’s possible this drug messes with your brain somehow that makes it more likely you’ll kill yourself. This drug is messing with a lot of things, and no one really understands what exactly it is doing. I reckon in the long run, the fallout is going to be a whole lot more severe than a few suicides. Whether it’s cancer, birth defects, brain degradation, I don’t know, but I can pretty well guarantee the results of this drug will be a real nightmare.

CNN:

People taking semaglutide, the popular medication for diabetes and weight loss, are more likely to report having thoughts of suicide compared with those taking other drugs, according to a new study of an international drug safety database. But the finding is the latest see-saw of scientific evidence on the risk of depression and suicide tied to the popular medications — and critics say evidence that the drugs cause problems with mood is limited.

Semaglutide is sold under the brand name Ozempic when it’s prescribed for diabetes and Wegovy when it’s prescribed for weight loss.

There is no good reason for the drug to have two different names. It’s the same thing.

The reason they give it two names is related to liability. Also, if one of these drugs starts getting a bad name, they will try to keep selling the other one as long as they can. Then eventually, they will come out with a new, slightly different version that is also basically the same thing. (Prozac went through this whole process when it was revealed it was turning people into total psychopaths; drugs that are more or less exactly the same as Prozac are still on the market.)

In addition, a number of companies make compounded forms of the drug. The use of the medication has surged in recent years, and studies have shown more promising effects, including reductions in kidney disease and cancer.

But suicide has been a long-standing concern with medications that alter the desire for food. For some people, losing the pleasure and reward of eating — and perhaps other things — creates a dramatic shift in mood and may increase the risk of self-harm. In 2008, the weight loss drug rimonabant, which acted on the same brain system that gives people the munchies when they’re on marijuana, was withdrawn from use because it increased the risk of suicide. (The drug was never approved for use in the United States.)

The patient information for semaglutide already includes a warning to watch out for depression and suicidal thoughts. But there’s been conflicting evidence about the risk of suicidal thoughts and feelings with new weight loss drugs, including semaglutide.

…

The new study, which was published Tuesday in the journal JAMA Network Open, looked at reports of suicidal thoughts in people taking semaglutide — whether for diabetes or weight loss — in a database maintained by the World Health Organization that compiles adverse events linked to drugs across 140 countries.

…

The study authors found what they describe as a disproportional risk of suicidal thoughts in people taking semaglutide but not in people who were taking liraglutide. When they compared reports of suicidal thoughts in people taking semaglutide with the risk reported with all other drugs in the database, they found that the risk was elevated by about 45% in people taking semaglutide.

The risk was about four times higher in people who were also taking drugs to control depression and anxiety, suggesting that this group may be at even higher risk for mood effects with these medications.

Yeah, people are on all kinds of pills these days, having all kinds of problems.

Good luck to them.

It’s not really my problem.

Things are tough all over, and if you’re on pills for obesity and depression, maybe you should have made better decisions.

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