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Very cool preliminary findings suggest that women can take 5 mg of rapamycin once a week without serious side-effects.
We know from animal studies that rapamycin can extend female reproductive longevity—the next step is to find out if it means women can have kids for longer too! pic.twitter.com/ReT3Bib7a0
— Andrew Steele (@statto) July 22, 2024
Okay so say you believe all this feminist bullshit. Okay.
Why can’t women get married to an older man at 16, have 3-4 kids, then go to university in their mid-to-late twenties while the kids are also going to elementary school, then start work when the kids are teenagers and can look after themselves for the three hours between when they come home from school and mom gets off work?
Wouldn’t that solve both the problem of the birthrate and keep women in the workforce?
Instead we have this shit?
A drug that could extend women’s fertility by five years – and help them live longer in better health – is safe for a young, healthy population, according to early results of a study.
The research into repurposing the immunosuppressant rapamycin has been hailed a “paradigm shift” in how menopause is studied.
The Validating Benefits of Rapamycin for Reproductive Aging Treatment (Vibrant) study is designed to measure whether the drug can slow ovaries ageing, thereby delaying menopause, extending fertility and reducing the risk of age-related diseases.
The study, which will eventually include more than 1,000 women, now has 34 participants aged up to 35, with more women joining every day.
Yousin Suh, a professor of reproductive sciences and professor of genetics and development at Columbia University and Zev Williams, associate professor of women’s health and the chief of the division of reproductive endocrinology and infertility at Columbia University Irving Medical Center, co-led on the study.
Suh said early results suggested it was realistic to hope the drug could decrease ovary ageing by 20% without women experiencing any of the 44 side-effects rapamycin can have, which range from mild nausea and headaches to high blood pressure and infections.
In fact, Suh said, participants in the randomised, placebo-controlled study had self-reported improvements in their health, memory, energy levels and in the quality of their skin and hair: health improvements consistent with other studies into rapamycin that have suggested the medication can increase lifespan by 9-14% while revitalising the immune system and organs that deteriorate in old age.
“The results of this study – the first in human history – are very, very exciting. It means that those with age-related fertility problems now have hope when before, they didn’t,” said Suh.
“These early results mean we now have a clear shot at our ultimate goal: using rapamycin to extend the lifespan of the ovary and thereby delaying the menopause, while also extending the lifespan of the woman and improving her health and quality of life.”
…
Vibrant will report in two years and be followed up by a much bigger, “phase 2” study. “Our vision is women in their 30s and older can make a simple visit to their family doctor if they want to have more freedom over when they have babies,” said Suh.
Ridiculous.
After 3 years of planning and fundraising, my Rapamycin & Exercise human trial is ready to start patient recruitment!
The study enrolment link is in the pinned comment
Thank you all for being so supportive, particularly:
– Matt Kaeberlein @mkaeberlein for help with the study… pic.twitter.com/FEyGJHegAx— Dr Brad Stanfield (@BradStanfieldMD) July 21, 2024
